What is a common characteristic of patients with Addison's disease?

Study for the Physician Assistant Clinical Knowledge Rating and Assessment Tool (PACKRAT) 5 Test. Use our interactive quizzes with hints and explanations to get exam-ready!

A common characteristic of patients with Addison's disease is hyperpigmentation. This occurs due to increased levels of adrenocorticotropic hormone (ACTH), which stimulates melanocyte activity leading to an overproduction of melanin. This can cause darkening of the skin, particularly in areas exposed to sunlight, as well as in certain mucous membranes and pressure points.

In contrast, increased weight is generally not associated with Addison's disease, as the condition often leads to weight loss and decreased appetite due to insufficient cortisol production. Stable blood pressure is not characteristic either because patients commonly experience hypotension and may have difficulties maintaining normal blood pressure levels as cortisol influences vascular tone. Elevated cortisol levels also do not align with Addison's disease, as the condition is characterized by insufficient production of cortisol due to adrenal gland dysfunction.

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