What is the initial treatment of choice for hyperthyroidism in a 10-week pregnant patient?

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In the context of hyperthyroidism during pregnancy, Propylthiouracil (PTU) is the initial treatment of choice, particularly in the first trimester. PTU is preferred because it has a lower risk of teratogenic effects compared to methimazole and is effective in managing hyperthyroid symptoms. Additionally, PTU effectively inhibits the synthesis of thyroid hormones and prevents the conversion of thyroxine (T4) to triiodothyronine (T3), helping to stabilize the patient's thyroid function while minimizing potential harm to both the mother and the developing fetus.

During the first trimester, the developing fetal organs are particularly vulnerable, making the use of medications that have been associated with birth defects a significant concern. PTU has a longer safety record in early pregnancy, which is why it is the recommended choice for initial management of hyperthyroidism in pregnant patients.

The other treatment options presented do not align with the standard practices for managing hyperthyroidism in a pregnant patient. For example, no treatment would not be appropriate as unmanaged hyperthyroidism can lead to severe complications for both the mother and fetus. Radioiodine treatment is contraindicated in pregnancy due to the risk of fetal thyroid ablation and subsequent hypothyroidism. Subtotal

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