Where is hairy leukoplakia most commonly found in the oral cavity?

Hairy leukoplakia is most commonly found on the lateral aspects of the tongue. This condition is often associated with Epstein-Barr Virus (EBV) infection and is seen primarily in immunocompromised individuals, such as those with HIV/AIDS. The appearance of hairy leukoplakia is characterized by white, corrugated lesions that typically manifest in the oral cavity, particularly on the tongue. The lateral tongue is a favored site due to its unique combination of moist mucosal environment and the presence of EBV, which tends to produce this distinct manifestation.

While lesions can occur in other parts of the oral cavity, such as the palate, floor of the mouth, and gingiva, these sites are not as common for hairy leukoplakia compared to the lateral tongue, where the presentation is more typically observed.