Which clinical manifestation is characteristic of cocaine intoxication?

Study for the Physician Assistant Clinical Knowledge Rating and Assessment Tool (PACKRAT) 5 Test. Use our interactive quizzes with hints and explanations to get exam-ready!

Cocaine intoxication is typically associated with sympathomimetic effects, which stimulate the sympathetic nervous system. This results in several characteristic clinical manifestations, most notably tachycardia (increased heart rate) and hypertension (increased blood pressure). Cocaine acts as a potent stimulant, leading to increased energetic states and heightened alertness, which are reflective of elevated cardiovascular functioning.

Tachycardia is often observed as the heart rate increases in response to the stimulating effects of the drug, while hypertension occurs as blood vessels constrict due to the increased adrenergic activity. This combination of increased heart rate and elevated blood pressure is a hallmark of acute cocaine use and intoxication, differentiating it from other substances that may cause differing cardiovascular responses.

The other manifestations and conditions listed do not align with the expected effects of cocaine. For example, bradycardia and hypotension are more commonly associated with various depressants, while constricted pupils and drowsiness are not typical responses seen in cocaine intoxication, which usually displays dilated pupils and alertness rather than sedation. Understanding these distinct pharmacological effects is crucial for accurate diagnosis and management of patients presenting with substance use issues.

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