Which condition is characterized by linear ulcerations with transverse fissures?

Crohn's disease is characterized by linear ulcerations with transverse fissures in the gastrointestinal tract. This reflects the nature of the inflammation associated with Crohn's, which can cause both deep mucosal ulceration and a "cobblestone" appearance of the affected areas. These linear ulcerations are a distinctive feature of the disease and can occur anywhere from the mouth to the anus, though they most commonly affect the distal ileum and colon.

In Crohn's disease, the inflammation can penetrate deeper layers of the bowel wall and create fissures, which are sharp, crack-like cuts that can lead to complications such as abscesses and fistulas. This contrasts with other conditions listed, such as ulcerative colitis, which typically presents with continuous lesions and does not typically produce the same fissured appearance.