Which of the following is a common feature of osteoarthritis, particularly when treated with hyaluronic acid?

When discussing the management of osteoarthritis with treatments like hyaluronic acid injections, a notable characteristic is the long-duration of activity that these treatments can offer. Hyaluronic acid is naturally found in joint fluid and is used to supplement this fluid in osteoarthritic joints, aiming to improve lubrication and reduce pain.

The long-duration of activity refers to the sustained relief of symptoms that can occur after injection. Patients may experience a gradual improvement in joint function and a reduction in pain that can last several months, making it a favorable option for those looking for longer-lasting relief.

Other options, such as rapid onset of action, are not typically associated with hyaluronic acid treatments, as the improvement may take time to manifest. Severe side effects and a high risk of infection are generally not common with this treatment; hyaluronic acid is considered relatively safe for use in managed cases of osteoarthritis. Overall, the long-duration effect of treatment aligns well with the therapeutic goals for osteoarthritis management.